Recent executive orders and memoranda issued since the Trump administration began in January 2025, have had an immediate impact on organizations that contract with the federal government and there will be more changes to come. John Prairie and Kevin Maynard, partners at Wiley, discussed changes made by the new administration that impact government contractors in a session at the Society of Corporate Compliance and Ethics Government Contracting Compliance & Ethics Conference held at the end of February 2025. This article distills their insights. See “Understanding and Mitigating Risk of Organizational Conflicts of Interest for Government Vendors” (Mar. 13, 2024).